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how do Istio Gateway ,VirtualService ,DestinationRule works together to full fill a request

I have a app running on k8s with istio as service mesh and nginx as ingress controller. I was wondering what would be the request flow to my service .

is it possibly like ::

user-request -->istio_gateway --> istio_virtualServive --> istio_destinationRoute --> nginx_ingress --> service_pod .

thanks.Looking forward to some suggestions and insights.